PrimePCR™ ddPCR™ Expression Probe Assay: ACE, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031511; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5056170
Chromosome Location:   17:61562709-61564027question
Amplicon Length:   105

Gene Information

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified and two most abundant spliced variants encode the somatic form and the testicular form respectively that are equally active. [provided by RefSeq May 2010]

Gene Symbol:   ACE
Gene Name:   angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Aliases:   ACE1, CD143, DCP, DCP1, MGC26566, MVCD3
RefSeq:   NC_000017.10 NG_011648.1 NT_010783.15
Ensembl:   ENSG00000159640
Entrez:   1636
UniGene:   Hs.298469
Chromosome Mapping:   17q23.3

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