PrimePCR™ ddPCR™ Expression Probe Assay: FBXW2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0031415; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5056005
Chromosome Location:   9:123533688-123535079question
Amplicon Length:   126

Gene Information

F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact F-box proteins are one of the four subunits of ubiquitin protein ligases called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats leucine-rich repeats or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats. [provided by RefSeq Jul 2008]

Gene Symbol:   FBXW2
Gene Name:   F-box and WD repeat domain containing 2
Aliases:   FBW2, Fwd2, MGC117371, Md6
RefSeq:   NC_000009.11 NT_008470.19
Ensembl:   ENSG00000119402
Entrez:   26190
UniGene:   Hs.494985
Chromosome Mapping:   9q34

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