PrimePCR™ ddPCR™ Expression Probe Assay: CA9, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031395; Intron-spanning

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5055974
Chromosome Location:   9:35677787-35679268question
Amplicon Length:   124

Gene Information

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes including respiration calcification acid-base balance bone resorption and the formation of aqueous humor cerebrospinal fluid saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization however radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq Jul 2008]

Gene Symbol:   CA9
Gene Name:   carbonic anhydrase IX
Aliases:   CAIX, MN
RefSeq:   NC_000009.11 NG_011620.1 NT_008413.18
Ensembl:   ENSG00000107159
Entrez:   768
UniGene:   Hs.63287
Chromosome Mapping:   9p12

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