PrimePCR™ ddPCR™ Expression Probe Assay: PCSK1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031391; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5055966
Chromosome Location:   5:95730653-95733116question
Amplicon Length:   124

Gene Information

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin prorenin proenkephalin prodynorphin prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq Apr 2010]

Gene Symbol:   PCSK1
Gene Name:   proprotein convertase subtilisin/kexin type 1
Aliases:   BMIQ12, NEC1, PC1, PC3, SPC3
RefSeq:   NC_000005.9 NG_021161.1 NT_034772.6
Ensembl:   ENSG00000175426
Entrez:   5122
UniGene:   Hs.78977
Chromosome Mapping:   5q15-q21

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