PrimePCR™ ddPCR™ Expression Probe Assay: HSPB8, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031389; Intron-spanning

Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5055962
Chromosome Location:   12:119624848-119631577question
Amplicon Length:   90

Gene Information

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells and this protein also functions as a chaperone in association with Bag3 a stimulator of macroautophagy. Thus this gene appears to be involved in regulation of cell proliferation apoptosis and carcinogenesis and mutations in this gene have been associated with different neuromuscular diseases including Charcot-Marie-Tooth disease. [provided by RefSeq Jul 2008]

Gene Symbol:   HSPB8
Gene Name:   heat shock 22kDa protein 8
Aliases:   CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
RefSeq:   NC_000012.11 NG_007953.1 NT_009775.17
Ensembl:   ENSG00000152137
Entrez:   26353
UniGene:   Hs.400095
Chromosome Mapping:   12q24.23

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