PrimePCR™ ddPCR™ Expression Probe Assay: ABHD12, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0031387; Intron-spanning

Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5055959
Chromosome Location:   20:25300878-25304045question
Amplicon Length:   132

Gene Information

This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG) the main endocannabinoid lipid transmitter that acts on cannabinoid receptors CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes including neurotransmission mood appetite pain appreciation addiction behavior and inflammation. Mutations in this gene are associated with the neurodegenerative disease PHARC (polyneuropathy hearing loss ataxia retinitis pigmentosa and cataract) resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq Jan 2011]

Gene Symbol:   ABHD12
Gene Name:   abhydrolase domain containing 12
Aliases:   ABHD12A, BEM46L2, C20orf22, DKFZp434P106, PHARC, dJ965G21.2
RefSeq:   NC_000020.10 NT_011387.8 NG_028119.1
Ensembl:   ENSG00000100997
Entrez:   26090
UniGene:   Hs.441550
Chromosome Mapping:   20p11.21

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