PrimePCR™ ddPCR™ Expression Probe Assay: EIF2AK3, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0031378; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5055945
Chromosome Location:   2:88890519-88892912question
Amplicon Length:   145

Gene Information

The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2) leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER) where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq Jan 2010]

Gene Symbol:   EIF2AK3
Gene Name:   eukaryotic translation initiation factor 2-alpha kinase 3
Aliases:   DKFZp781H1925, PEK, PERK, WRS
RefSeq:   NC_000002.11 NG_016424.1 NT_022184.15
Ensembl:   ENSG00000172071
Entrez:   9451
UniGene:   Hs.591589
Chromosome Mapping:   2p12

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