PrimePCR™ ddPCR™ Expression Probe Assay: NLRP13, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0030154; Intron-spanning

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5053635
Chromosome Location:   19:56424590-56435988question
Amplicon Length:   139

Gene Information

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs such as NALP13 have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD) followed by a NACHT domain a NACHT-associated domain (NAD) and a C-terminal leucine-rich repeat (LRR) region. The long NALP NALP1 (MIM 606636) also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g. CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al. 2003 [PubMed 12563287]).[supplied by OMIM Mar 2008]

Gene Symbol:   NLRP13
Gene Name:   NLR family, pyrin domain containing 13
Aliases:   CLR19.7, NALP13, NOD14, PAN13
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000173572
Entrez:   126204
UniGene:   Hs.446924
Chromosome Mapping:   19q13.43

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