PrimePCR™ ddPCR™ Expression Probe Assay: TRAF3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0030072; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5053472
Chromosome Location:   14:103363623-103369647question
Amplicon Length:   142

Gene Information

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with and mediate the signal transduction from members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40 a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq Dec 2010]

Gene Symbol:   TRAF3
Gene Name:   TNF receptor-associated factor 3
Aliases:   CAP-1, CD40bp, CRAF1, LAP1
RefSeq:   NC_000014.8 NT_026437.12 NG_027973.1
Ensembl:   ENSG00000131323
Entrez:   7187
UniGene:   Hs.510528
Chromosome Mapping:   14q32.32

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