PrimePCR™ ddPCR™ Expression Probe Assay: POF1B, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0029980; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5053300
Chromosome Location:   X:84614572-84634209question
Amplicon Length:   141

Gene Information

Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called "POF1" and "POF2" have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene POF1B resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined. [provided by RefSeq Jan 2010]

Gene Symbol:   POF1B
Gene Name:   premature ovarian failure, 1B
Aliases:   FLJ22792, POF, POF2B
RefSeq:   NC_000023.10 NG_016358.1 NT_011651.17
Ensembl:   ENSG00000124429
Entrez:   79983
UniGene:   Hs.267038
Chromosome Mapping:   Xq21.2

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