PrimePCR™ ddPCR™ Expression Probe Assay: PAK7, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029967; Intron-spanning

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5053277
Chromosome Location:   20:9546878-9560813question
Amplicon Length:   146

Gene Information

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases which have been implicated in the regulation of cytoskeletal dynamics proliferation and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq Jul 2008]

Gene Symbol:   PAK7
Gene Name:   p21 protein (Cdc42/Rac)-activated kinase 7
Aliases:   KIAA1264, MGC26232, PAK5
RefSeq:   NC_000020.10 NT_011387.8
Ensembl:   ENSG00000101349
Entrez:   57144
UniGene:   Hs.32539
Chromosome Mapping:   20p12

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