This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0029963; Intron-spanning
The protein encoded by this gene binds to the cytoplasmic tail of CD2 an effector of T cell activation and adhesion negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1 PTPN18 WAS CD2AP and PTPN12. Mutations in this gene are a cause of PAPA syndrome. [provided by RefSeq Jul 2008]