PrimePCR™ ddPCR™ Expression Probe Assay: MEP1B, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029834; Intron-spanning

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5053041
Chromosome Location:   18:29793465-29795091question
Amplicon Length:   75

Gene Information

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted whereas oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability renal gene expression profiles and distribution of the membrane-associated alpha subunit in kidney and intestine. [provided by RefSeq Oct 2011]

Gene Symbol:   MEP1B
Gene Name:   meprin A, beta
Aliases:   Not Available
RefSeq:   NC_000018.9 NT_010966.14
Ensembl:   ENSG00000141434
Entrez:   4225
UniGene:   Hs.194777
Chromosome Mapping:   18q12.2-q12.3

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