PrimePCR™ ddPCR™ Expression Probe Assay: WNT3, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029773; Intron-spanning

Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052927
Chromosome Location:   17:44841923-44845745question
Amplicon Length:   103

Gene Information

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein and 84% to human WNT3A protein another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast rectal lung and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15 another family member in the chromosome 17q21 region. [provided by RefSeq Jul 2008]

Gene Symbol:   WNT3
Gene Name:   wingless-type MMTV integration site family, member 3
Aliases:   INT4, MGC131950, MGC138321, MGC138323
RefSeq:   NC_000017.10 NG_008084.1 NT_010783.15
Ensembl:   ENSG00000108379
Entrez:   7473
UniGene:   Hs.445884
Chromosome Mapping:   17q21

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