PrimePCR™ ddPCR™ Expression Probe Assay: CYP1A2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029751; Intron-spanning

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052883
Chromosome Location:   15:75045562-75047256question
Amplicon Length:   145

Gene Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs) some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine aflatoxin B1 and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq Jul 2008]

Gene Symbol:   CYP1A2
Gene Name:   cytochrome P450, family 1, subfamily A, polypeptide 2
Aliases:   CP12, P3-450, P450(PA)
RefSeq:   NC_000015.9 NG_008431.1 NT_010194.17
Ensembl:   ENSG00000140505
Entrez:   1544
UniGene:   Hs.1361
Chromosome Mapping:   15q24.1

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