PrimePCR™ ddPCR™ Expression Probe Assay: CYBB, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0029732; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052846
Chromosome Location:   X:37660517-37663174question
Amplicon Length:   100

Gene Information

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq Jul 2008]

Gene Symbol:   CYBB
Gene Name:   cytochrome b-245, beta polypeptide
Aliases:   CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX
RefSeq:   NC_000023.10 NG_009065.1 NT_079573.4
Ensembl:   ENSG00000165168
Entrez:   1536
UniGene:   Hs.292356
Chromosome Mapping:   Xp21.1

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