PrimePCR™ ddPCR™ Expression Probe Assay: TEK, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029718; Intron-spanning

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052819
Chromosome Location:   9:27183566-27185570question
Amplicon Length:   101

Gene Information

The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice rats and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. [provided by RefSeq Jul 2008]

Gene Symbol:   TEK
Gene Name:   TEK tyrosine kinase, endothelial
Aliases:   CD202B, TIE-2, TIE2, VMCM, VMCM1
RefSeq:   NC_000009.11 NG_011828.1 NT_008413.18
Ensembl:   ENSG00000120156
Entrez:   7010
UniGene:   Hs.89640
Chromosome Mapping:   9p21

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