PrimePCR™ ddPCR™ Expression Probe Assay: ABCB7, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029632; Intron-spanning

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052671
Chromosome Location:   X:74290296-74291451question
Amplicon Length:   140

Gene Information

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia. [provided by RefSeq Jul 2008]

Gene Symbol:   ABCB7
Gene Name:   ATP-binding cassette, sub-family B (MDR/TAP), member 7
Aliases:   ABC7, ASAT, Atm1p, EST140535
RefSeq:   NC_000023.10 NG_007980.1 NT_011669.17
Ensembl:   ENSG00000131269
Entrez:   22
UniGene:   Hs.370480
Chromosome Mapping:   Xq13.3

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