PrimePCR™ ddPCR™ Expression Probe Assay: RRBP1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029628; Intron-spanning

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052663
Chromosome Location:   20:17601397-17602174question
Amplicon Length:   98

Gene Information

This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation secretory pathways and secretory cell differentiation and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7 and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome the result of a mutation in a nearby gene on chromosome 20p12. [provided by RefSeq Apr 2012]

Gene Symbol:   RRBP1
Gene Name:   ribosome binding protein 1 homolog 180kDa (dog)
Aliases:   DKFZp586A1420, ES/130, ES130, FLJ36146, MGC157720, MGC157721, hES
RefSeq:   NC_000020.10 NT_011387.8
Ensembl:   ENSG00000125844
Entrez:   6238
UniGene:   Hs.472213
Chromosome Mapping:   20p12

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