PrimePCR™ ddPCR™ Expression Probe Assay: COL17A1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029613; Intron-spanning

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052639
Chromosome Location:   10:105797394-105798199question
Amplicon Length:   144

Gene Information

This gene encodes the alpha chain of type XVII collagen. Unlike most collagens collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form referred to as either ectodomain or LAD-1 is generated by proteolytic processing of the full length form. [provided by RefSeq Jul 2008]

Gene Symbol:   COL17A1
Gene Name:   collagen, type XVII, alpha 1
Aliases:   BA16H23.2, BP180, BPAG2, FLJ60881, KIAA0204, LAD-1
RefSeq:   NC_000010.10 NG_007069.1 NT_030059.13
Ensembl:   ENSG00000065618
Entrez:   1308
UniGene:   Hs.117938
Chromosome Mapping:   10q24.3

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