PrimePCR™ ddPCR™ Expression Probe Assay: CDK8, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0029598; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052614
Chromosome Location:   13:26971290-26974670question
Amplicon Length:   124

Gene Information

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28 and Schizosaccharomyces pombe cdc2 and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH) thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery. [provided by RefSeq Jul 2008]

Gene Symbol:   CDK8
Gene Name:   cyclin-dependent kinase 8
Aliases:   K35, MGC126074, MGC126075
RefSeq:   NC_000013.10 NT_024524.14
Ensembl:   ENSG00000132964
Entrez:   1024
UniGene:   Hs.382306
Chromosome Mapping:   13q12

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