PrimePCR™ ddPCR™ Expression Probe Assay: SYN3, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029520; Intron-spanning

Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052483
Chromosome Location:   22:33327407-33376673question
Amplicon Length:   74

Gene Information

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains and they are implicated in synaptogenesis and the modulation of neurotransmitter release suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model with domains A C and E exhibiting the highest degree of conservation. The protein contains a unique domain J located between domains C and E. Based on this gene's localization to 22q12.3 a possible schizophrenia susceptibility locus and the established neurobiological roles of the synapsins this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite direction. Alternative splicing of this gene results in multiple splice variants that encode different isoforms. [provided by RefSeq Oct 2008]

Gene Symbol:   SYN3
Gene Name:   synapsin III
Aliases:   Not Available
RefSeq:   NG_009117.1 NC_000022.10 NT_011520.12
Ensembl:   ENSG00000185666
Entrez:   8224
UniGene:   Hs.608750
Chromosome Mapping:   22q12.3

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