PrimePCR™ ddPCR™ Expression Probe Assay: ACTL6A, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029518; Intron-spanning

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052479
Chromosome Location:   3:179304347-179305775question
Amplicon Length:   102

Gene Information

This gene encodes a family member of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold which is an ATP-binding cleft as a common feature. The ARPs are involved in diverse cellular processes including vesicular transport spindle orientation nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin it is required for maximal ATPase activity of BRG1 and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq Jul 2008]

Gene Symbol:   ACTL6A
Gene Name:   actin-like 6A
Aliases:   ACTL6, ARPN-BETA, Arp4, BAF53A, INO80K, MGC5382
RefSeq:   NC_000003.11 NT_005612.16
Ensembl:   ENSG00000136518
Entrez:   86
UniGene:   Hs.435326
Chromosome Mapping:   3q26.33

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