PrimePCR™ ddPCR™ Expression Probe Assay: WNT1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029498; Intron-spanning

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052441
Chromosome Location:   12:49373463-49374311question
Amplicon Length:   117

Gene Information

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member WNT10B in the chromosome 12q13 region. [provided by RefSeq Jul 2008]

Gene Symbol:   WNT1
Gene Name:   wingless-type MMTV integration site family, member 1
Aliases:   INT1
RefSeq:   NC_000012.11 NT_029419.12
Ensembl:   ENSG00000125084
Entrez:   7471
UniGene:   Hs.248164
Chromosome Mapping:   12q13

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