PrimePCR™ ddPCR™ Expression Probe Assay: MASP1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029477; Intron-spanning

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052409
Chromosome Location:   3:186974509-186978565question
Amplicon Length:   147

Gene Information

This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq Apr 2010]

Gene Symbol:   MASP1
Gene Name:   mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
Aliases:   CRARF, CRARF1, DKFZp686I01199, FLJ26383, MAP1, MASP, MASP3, MAp44, MGC126283, MGC126284, PRSS5, RaRF
RefSeq:   NC_000003.11 NT_005612.16
Ensembl:   ENSG00000127241
Entrez:   5648
UniGene:   Hs.89983
Chromosome Mapping:   3q27-q28

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