PrimePCR™ ddPCR™ Expression Probe Assay: LILRB2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0029475; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5052404
Chromosome Location:   19:54778538-54779844question
Amplicon Length:   156

Gene Information

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains a transmembrane domain and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   LILRB2
Gene Name:   leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
Aliases:   CD85D, ILT4, LILRA6, LIR-2, LIR2, MIR-10, MIR10
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000131042
Entrez:   10288
UniGene:   Hs.655652
Chromosome Mapping:   19q13.4

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