PrimePCR™ ddPCR™ Expression Probe Assay: COL18A1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0028389; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5050622
Chromosome Location:   21:46896316-46897360question
Amplicon Length:   85

Gene Information

This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Sep 2008]

Gene Symbol:   COL18A1
Gene Name:   collagen, type XVIII, alpha 1
Aliases:   FLJ27325, FLJ34914, KNO, KNO1, KS, MGC74745
RefSeq:   NC_000021.8 NT_011515.12 NG_011903.1
Ensembl:   ENSG00000182871
Entrez:   80781
UniGene:   Hs.517356
Chromosome Mapping:   21q22.3

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