PrimePCR™ ddPCR™ Expression Probe Assay: KANK1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0028329; Intron-spanning

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5050516
Chromosome Location:   9:738475-740904question
Amplicon Length:   113

Gene Information

The protein encoded by this gene belongs to the Kank family of proteins which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2 a central nervous system development disorder. A t(5;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseuodgene has been identified on chromosome 20. [provided by RefSeq Mar 2012]

Gene Symbol:   KANK1
Gene Name:   KN motif and ankyrin repeat domains 1
Aliases:   ANKRD15, DKFZp451G231, KANK, KIAA0172, MGC43128
RefSeq:   NC_000009.11 NG_016331.1 NT_008413.18
Ensembl:   ENSG00000107104
Entrez:   23189
UniGene:   Hs.306764
Chromosome Mapping:   9p24.3

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