PrimePCR™ ddPCR™ Expression Probe Assay: BACE2, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0028327; Intron-spanning

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5050513
Chromosome Location:   21:42598193-42609478question
Amplicon Length:   98

Gene Information

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein a member of the peptidase A1 protein family is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   BACE2
Gene Name:   beta-site APP-cleaving enzyme 2
Aliases:   AEPLC, ALP56, ASP1, ASP21, BAE2, CEAP1, DRAP
RefSeq:   NC_000021.8 NT_011512.11
Ensembl:   ENSG00000182240
Entrez:   25825
UniGene:   Hs.529408
Chromosome Mapping:   21q22.3

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