PrimePCR™ ddPCR™ Expression Probe Assay: CTSE, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0028222; Intron-spanning

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5050335
Chromosome Location:   1:206319119-206320255question
Amplicon Length:   125

Gene Information

The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease which is a member of the peptidase C1 family has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears therefore to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   CTSE
Gene Name:   cathepsin E
Aliases:   CATE
RefSeq:   NC_000001.10 NT_086602.2
Ensembl:   ENSG00000196188
Entrez:   1510
UniGene:   Hs.644082
Chromosome Mapping:   1q31

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