PrimePCR™ ddPCR™ Expression Probe Assay: CYP46A1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0028120; Intron-spanning

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5050161
Chromosome Location:   14:100182251-100184449question
Amplicon Length:   139

Gene Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq Jul 2008]

Gene Symbol:   CYP46A1
Gene Name:   cytochrome P450, family 46, subfamily A, polypeptide 1
Aliases:   CP46, CYP46
RefSeq:   NC_000014.8 NG_007963.1 NT_026437.12
Ensembl:   ENSG00000036530
Entrez:   10858
UniGene:   Hs.25121
Chromosome Mapping:   14q32.1

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