PrimePCR™ ddPCR™ Expression Probe Assay: CCL5, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0028116; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5050154
Chromosome Location:   17:34199344-34205572question
Amplicon Length:   136

Gene Information

This gene is one of several CC cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene functions as a chemoattractant for blood monocytes memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor CCR5 and it suppresses in vitro replication of the R5 strains of HIV-1 which use CCR5 as a coreceptor. [provided by RefSeq Jul 2008]

Gene Symbol:   CCL5
Gene Name:   chemokine (C-C motif) ligand 5
Aliases:   D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228
RefSeq:   NC_000017.10 NG_015990.1 NT_010799.15
Ensembl:   ENSG00000161570
Entrez:   6352
UniGene:   Hs.514821
Chromosome Mapping:   17q11.2-q12

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