PrimePCR™ ddPCR™ Expression Probe Assay: SCD5, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0028087; Intron-spanning

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5050098
Chromosome Location:   4:83626440-83719487question
Amplicon Length:   126

Gene Information

Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms Scd1 through Scd4 have been identified in mouse. In contrast only 2 SCD isoforms SCD1 (MIM 604031) and SCD5 have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms as well as with rat Scd1 and Scd2. In contrast SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al. 2005 [PubMed 15907797]).[supplied by OMIM Mar 2008]

Gene Symbol:   SCD5
Gene Name:   stearoyl-CoA desaturase 5
Aliases:   ACOD4, FADS4, FLJ21032, HSCD5, SCD2, SCD4
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000145284
Entrez:   79966
UniGene:   Hs.379191
Chromosome Mapping:   4q21.22

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