PrimePCR™ ddPCR™ Expression Probe Assay: IL24, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0028058; Intron-spanning

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5050050
Chromosome Location:   1:207075343-207076391question
Amplicon Length:   116

Gene Information

This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38) and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq Jul 2008]

Gene Symbol:   IL24
Gene Name:   interleukin 24
Aliases:   C49A, FISP, IL10B, MDA7, MOB5, ST16
RefSeq:   NC_000001.10 NT_167186.1
Ensembl:   ENSG00000162892
Entrez:   11009
UniGene:   Hs.732513
Chromosome Mapping:   1q32

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