This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0028031; Intron-spanning
This gene encodes a mitochondrial protein that is a member of the solute carrier family. Although this protein was initially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into the matrix of the mitochondria further studies have demonstrated that this protein instead functions as the mitochondrial thiamine pyrophosphate carrier which transports thiamine pyrophosphates into mitochondria. Mutations in this gene cause microcephaly Amish type a metabolic disease that results in severe congenital microcephaly severe 2-ketoglutaric aciduria and death within the first year. Multiple alternatively spliced variants encoding the same protein have been identified for this gene. [provided by RefSeq Jul 2008]