PrimePCR™ ddPCR™ Expression Probe Assay: HGF, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0028019; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5049982
Chromosome Location:   7:81388022-81392081question
Amplicon Length:   128

Gene Information

Hepatocyte growth factor regulates cell growth cell motility and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis cell motility and matrix invasion gives it a central role in angiogenesis tumorogenesis and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   HGF
Gene Name:   hepatocyte growth factor (hepapoietin A; scatter factor)
Aliases:   DFNB39, F-TCF, HGFB, HPTA, SF
RefSeq:   NC_000007.13 NG_016274.1 NT_007933.15
Ensembl:   ENSG00000019991
Entrez:   3082
UniGene:   Hs.396530
Chromosome Mapping:   7q21.1

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