This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
ddPCR™ probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.
Info: FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027960; Intron-spanning
The protein encoded by this gene belongs to the GTPase-activating protein (GAP) family. GAPs bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function GAPs negatively regulate Rho-mediated signals. This protein plays a regulatory role in initiation of cytokinesis controlling cell growth and differentiation of hematopoietic cells regulating spermatogenesis and in neuronal proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq Sep 2011]