PrimePCR™ ddPCR™ Expression Probe Assay: MYH7, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0027920; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5049823
Chromosome Location:   14:23891477-23892840question
Amplicon Length:   113

Gene Information

Muscle myosin is a hexameric protein containing 2 heavy chain subunits 2 alkali light chain subunits and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy myosin storage myopathy dilated cardiomyopathy and Laing early-onset distal myopathy. [provided by RefSeq Jul 2008]

Gene Symbol:   MYH7
Gene Name:   myosin, heavy chain 7, cardiac muscle, beta
Aliases:   CMD1S, CMH1, DKFZp451F047, MGC138376, MGC138378, MPD1, MYHCB, SPMD, SPMM
RefSeq:   NC_000014.8 NG_007884.1 NG_023444.1 NT_026437.12
Ensembl:   ENSG00000092054
Entrez:   4625
UniGene:   Hs.719946
Chromosome Mapping:   14q12

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