PrimePCR™ ddPCR™ Expression Probe Assay: SLX4, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027868; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5049724
Chromosome Location:   16:3651145-3652251question
Amplicon Length:   151

Gene Information

This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1 MUS81-EME1 and SLX1 endonucleases and also associates with MSH2/MSH3 mismatch repair complex telomere binding complex TERF2(TRF2)-TERF2IP(RAP1) the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases.[provided by RefSeq Jan 2011]

Gene Symbol:   SLX4
Gene Name:   SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
Aliases:   BTBD12, FANCP, KIAA1784, KIAA1987, MUS312
RefSeq:   NC_000016.9 NG_028123.1 NT_010393.16
Ensembl:   ENSG00000188827
Entrez:   84464
UniGene:   Hs.143681
Chromosome Mapping:   16p13.3

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