PrimePCR™ ddPCR™ Expression Probe Assay: NRG1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027789; Intron-spanning

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5049590
Chromosome Location:   8:32611890-32613972question
Amplicon Length:   125

Gene Information

The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure and thereby these isoforms are classified into types I II III IV V and VI. The gene dysregulation has been linked to diseases such as cancer schizophrenia and bipolar disorder (BPD). [provided by RefSeq May 2009]

Gene Symbol:   NRG1
Gene Name:   neuregulin 1
Aliases:   ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, NDF, SMDF
RefSeq:   NC_000008.10 NT_167187.1 NG_012005.1
Ensembl:   ENSG00000157168
Entrez:   3084
UniGene:   Hs.453951
Chromosome Mapping:   8p12

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