PrimePCR™ ddPCR™ Expression Probe Assay: PLCG1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027760; Intron-spanning

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5049540
Chromosome Location:   20:39792767-39793677question
Amplicon Length:   150

Gene Information

The protein encoded by this gene catalyzes the formation of inositol 145-trisphosphate and diacylglycerol from phosphatidylinositol 45-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example when activated by SRC the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi where it activates Ras. Also this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   PLCG1
Gene Name:   phospholipase C, gamma 1
Aliases:   NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1
RefSeq:   NC_000020.10 NT_011362.10
Ensembl:   ENSG00000124181
Entrez:   5335
UniGene:   Hs.268177
Chromosome Mapping:   20q12-q13.1

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