PrimePCR™ ddPCR™ Expression Probe Assay: DNMT3A, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027759; Intron-spanning

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5049538
Chromosome Location:   2:25467441-25468163question
Amplicon Length:   93

Gene Information

CpG methylation is an epigenetic modification that is important for embryonic development imprinting and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   DNMT3A
Gene Name:   DNA (cytosine-5-)-methyltransferase 3 alpha
Aliases:   DNMT3A2, M.HsaIIIA
RefSeq:   NC_000002.11 NT_022184.15
Ensembl:   ENSG00000119772
Entrez:   1788
UniGene:   Hs.515840
Chromosome Mapping:   2p23

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