PrimePCR™ ddPCR™ Expression Probe Assay: C4BPB, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027757; Intron-spanning

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5049534
Chromosome Location:   1:207262883-207263744question
Amplicon Length:   111

Gene Information

This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also mediated through the beta-chain binding of protein S a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq Jul 2008]

Gene Symbol:   C4BPB
Gene Name:   complement component 4 binding protein, beta
Aliases:   C4BP
RefSeq:   NC_000001.10 NT_167186.1
Ensembl:   ENSG00000123843
Entrez:   725
UniGene:   Hs.99886
Chromosome Mapping:   1q32

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