PrimePCR™ ddPCR™ Expression Probe Assay: HUWE1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0027756; Intron-spanning

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5049533
Chromosome Location:   X:53619468-53620362question
Amplicon Length:   130

Gene Information

This gene encodes a member of the HECT E3 ubiquitin ligase family. The HECT domain lies in the C-terminus and contains the active-site cysteine which forms an intermediate ubiquitin-thioester bond. E3 family members are divided into three subfamilies based on their protein-protein interaction domains; this gene encodes a member of the SI(ngle)-HECT E3 subfamily. In lung breast and colorectal carcinomas this gene is highly expressed. Mutations in this gene has been found in 3 unrelated families with X-linked syndromic mental retardation Turner type. [provided by RefSeq Nov 2009]

Gene Symbol:   HUWE1
Gene Name:   HECT, UBA and WWE domain containing 1
Aliases:   ARF-BP1, HECTH9, HSPC272, Ib772, KIAA0312, LASU1, MULE, UREB1
RefSeq:   NC_000023.10 NG_016261.1 NT_011630.14
Ensembl:   ENSG00000086758
Entrez:   10075
UniGene:   Hs.136905
Chromosome Mapping:   Xp11.22

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