PrimePCR™ ddPCR™ Expression Probe Assay: NFASC, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027744; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5049510
Chromosome Location:   1:204921179-204923361question
Amplicon Length:   82

Gene Information

This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth neurite fasciculation and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein gliomedin ankyrin 3 (ankyrin-G) and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing and the full-length nature of some variants has not been determined.[provided by RefSeq May 2009]

Gene Symbol:   NFASC
Gene Name:   neurofascin
Aliases:   DKFZp686P2250, FLJ46866, KIAA0756, NF, NRCAML
RefSeq:   NC_000001.10 NT_004487.19
Ensembl:   ENSG00000163531
Entrez:   23114
UniGene:   Hs.13349
Chromosome Mapping:   1q32.1

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