PrimePCR™ ddPCR™ Expression Probe Assay: MECOM, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027711; Intron-spanning

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5049452
Chromosome Location:   3:168845810-168849279question
Amplicon Length:   72

Gene Information

The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis apoptosis development and cell differentiation and proliferation. The encoded protein can interact with CTBP1 SMAD3 CREBBP KAT2B MAPK8 and MAPK9. This gene can undergo translocation with the AML1 gene resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq Mar 2011]

Gene Symbol:   MECOM
Gene Name:   MDS1 and EVI1 complex locus
Aliases:   AML1-EVI-1, EVI1, MDS1, MDS1-EVI1, MGC163392, MGC97004, PRDM3
RefSeq:   NC_000003.11 NT_005612.16
Ensembl:   ENSG00000085276
Entrez:   2122
UniGene:   Hs.659873
Chromosome Mapping:   3q26

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