PrimePCR™ ddPCR™ Expression Probe Assay: SKP1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0027663; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5049358
Chromosome Location:   5:133502884-133512550question
Amplicon Length:   122

Gene Information

This gene encodes a component of SCF complexes which are composed of this protein cullin 1 a ring-box protein and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s) and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq Jul 2008]

Gene Symbol:   SKP1
Gene Name:   S-phase kinase-associated protein 1
Aliases:   EMC19, MGC34403, OCP-II, OCP2, SKP1A, TCEB1L, p19A
RefSeq:   NC_000005.9 NT_034772.6
Ensembl:   ENSG00000113558
Entrez:   6500
UniGene:   Hs.171626
Chromosome Mapping:   5q31

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