PrimePCR™ ddPCR™ Expression Probe Assay: PTPRK, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0027651; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5049339
Chromosome Location:   6:128505758-128540131question
Amplicon Length:   148

Gene Information

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitotic cycle and oncogenic transformation. This PTP possesses an extracellular region a single transmembrane region and two tandem catalytic domains and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1 which may be important for the inhibition of keratinocyte proliferation. [provided by RefSeq Jul 2008]

Gene Symbol:   PTPRK
Gene Name:   protein tyrosine phosphatase, receptor type, K
Aliases:   DKFZp686C2268, DKFZp779N1045, R-PTP-kappa
RefSeq:   NC_000006.11 NT_025741.15
Ensembl:   ENSG00000152894
Entrez:   5796
UniGene:   Hs.155919
Chromosome Mapping:   6q22.2-q22.3

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