PrimePCR™ ddPCR™ Expression Probe Assay: ATIC, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0027647; Intron-spanning

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5049331
Chromosome Location:   2:216209546-216211549question
Amplicon Length:   87

Gene Information

This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq Sep 2009]

Gene Symbol:   ATIC
Gene Name:   5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Aliases:   AICAR, AICARFT, FLJ93545, IMPCHASE, PURH
RefSeq:   NC_000002.11 NG_013002.1 NT_005403.17
Ensembl:   ENSG00000138363
Entrez:   471
UniGene:   Hs.90280
Chromosome Mapping:   2q35

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