PrimePCR™ ddPCR™ Expression Probe Assay: ARRB1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0027614; Intron-spanning

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5049269
Chromosome Location:   11:74988417-74989692question
Amplicon Length:   86

Gene Information

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones neurotransmitters or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system it is expressed at high levels in peripheral blood leukocytes and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq Jan 2011]

Gene Symbol:   ARRB1
Gene Name:   arrestin, beta 1
Aliases:   ARB1, ARR1
RefSeq:   NC_000011.9 NG_028118.1 NT_167190.1
Ensembl:   ENSG00000137486
Entrez:   408
UniGene:   Hs.503284
Chromosome Mapping:   11q13

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